Compartmental excision involves removing an entire anatomical region where defined structures act as natural barriers to tumour extension. While widely adopted in human oncology, the technique has been infrequently reported in veterinary practice. This study describes complete muscle resection performed in three dogs diagnosed with distinct intramuscular sarcomas and reports their clinical outcomes. Medical records were reviewed for preoperative findings, surgical details, histopathological results, and follow-up. All enrolled cases had sarcomas confined to a single muscle belly (semitendinosus, biceps brachii, and splenius capitis). Complete resection of the affected muscle was achieved in each dog. One dog developed transient moderate lameness postoperatively due to dorsal scapular displacement, attributed to serratus ventralis tenotomy required for removing the splenius capitis insertion. All dogs demonstrated full functional recovery within one month. Histopathology confirmed complete tumour excision with intact fascial boundaries in all cases. These findings suggest that compartmental excision can provide effective local tumour control and may serve as an alternative to limb amputation or more extensive surgery, particularly when radiotherapy is not feasible.
