TY  - JOUR
T1  - Flexible Fuel Use and Redox Regulation Coordinate Insect Survival Under Nutritional and Environmental Stress
A1  - Santiago Morales
A1  - Laura Rojas
A1  - Camila Vega
A1  - Diego Molina
JF  - Entomological Research Letters
JO  - Entomol Res Lett
SN  - 3108-639X
Y1  - 2022
VL  - 2
IS  - 2
DO  - 10.51847/bG6BOJYplA
SP  - 67
EP  - 77
N2  - Insects survive starvation, heat, and infection by reallocating substrates while maintaining cellular protection and repair. These processes are usually treated separately, obscuring that the value of a metabolic response depends on tissue demand, timing, physiological state, and damage-control capacity. This article develops a non-empirical physiological framework in which survival depends on coordination rather than maximal fuel release or indiscriminate suppression of reactive oxygen species (ROS). Evidence from Drosophila and selected lepidopteran and hemipteran systems shows rapid nutritional-state remodeling, regulated carbohydrate and lipid mobilization, amino-acid recycling and acquisition responses, and context-dependent redox signaling. The same literature identifies failure modes: dysregulated mobilization can accompany poorer starvation survival, sustained immune-driven release can deplete reserves, and redox effects vary by tissue, life stage, age, sex, and stress protocol. The proposed architecture therefore separates fuel availability, mobilization control, tissue demand, redox signaling, oxidative damage, and repair capacity. It is intended as a testable organizing framework, not a validated universal mechanism.
UR  - https://esvpub.com/article/flexible-fuel-use-and-redox-regulation-coordinate-insect-survival-under-nutritional-and-environmenta-6qukckj6jhojkqd
ER  -