TY  - JOUR
T1  - Alleles 177 (AC117), 263 (Ap243), and 269 (SV185) Confer Reduced Nosema Infection in Apis mellifera mellifera: Implications for Marker-Assisted Selection
A1  - Ivan Petrov
A1  - Anna Ivanova
A1  - Dmitry Sokolov
JF  - International Journal of Veterinary Research and Allied Sciences
JO  - Int J Vet Res Allied Sci
SN  - 3062-357X
Y1  - 2021
VL  - 1
IS  - 1
DO  - 10.51847/Iuj6c97t69
SP  - 50
EP  - 63
N2  - Microsporidian parasites of the genus Nosema, especially Nosema ceranae, continue to represent major threats to the health of Apis mellifera colonies. A promising strategy to mitigate these effects involves breeding honey bee colonies resistant to Nosema infection through molecular breeding methods such as marker-assisted selection (MAS). To enable this, it is necessary to establish reliable genetic markers for bee selection. This study aimed to investigate correlations between certain microsatellite loci and susceptibility to Nosema infection in the dark forest bee, Apis mellifera mellifera. Among the tested loci, AC117, Ap243, and SV185 were the most promising molecular markers associated with resistance to nosemosis. Their alleles “177,” “263,” and “269,” respectively, correlated with a lower infection level. This work represents the first associative investigation aimed at identifying DNA loci linked to resistance against nosemosis in dark forest bees. The discovered microsatellite markers may serve as predictive tools for estimating the likelihood of Nosema disease occurrence.
UR  - https://esvpub.com/article/alleles-177-ac117-263-ap243-and-269-sv185-confer-reduced-nosema-infection-in-apis-mellifera-cjnajezbrve1qf8
ER  -