TY - JOUR T1 - Mechanisms of Resistance to Beta-Cyfluthrin in the Cigarette Beetle, Lasioderma serricorne, and the Effectiveness of Imidacloprid Space Sprays A1 - James U. Alvarez A1 - James Clark A1 - Lucas Ferrari A1 - Paolo Z. Weber A1 - Ana I. Moore A1 - Diego K. Silva JF - Entomological Research Letters JO - Entomol Res Lett SN - 3108-639X Y1 - 2025 VL - 5 IS - 1 DO - 10.51847/BZZSnkes0yq0 SP - 1 EP - 11 N2 - Lasioderma serricorne (F.) (Coleoptera: Anobiidae) is widely recognized as the most harmful pest in the cigarette production industry. Beta-cyfluthrin, a synthetic pyrethroid, has long been used as an effective pesticide to control L. serricorne in cigarette and food processing facilities. This study aimed to evaluate the resistance of L. serricorne populations collected from the Hefei cigarette factory to beta-cyfluthrin and their response to imidacloprid, an alternative insecticide. The findings showed that the L. serricorne strain from Hefei exhibited significant resistance to beta-cyfluthrin but remained highly sensitive to imidacloprid, with a minimal cross-resistance ratio of 1.00-1.33. Further field trials showed that beta-cyfluthrin space sprays were ineffective in controlling the pests in the cigarette manufacturing area. In contrast, imidacloprid was highly effective, reducing the L. serricorne population by up to 100%. This study highlights the importance of early detection of insect resistance, the development of alternative pest control strategies, and the potential of imidacloprid as a viable option for the management of pyrethroid-resistant Coleoptera species. Furthermore, the results indicate that imidacloprid space sprays in confined spaces hold significant promise for the control of stored-product pests. UR - https://esvpub.com/article/JIUdFhZSm2SYe841EJsw ER -